Mercury-Induced Inhibition of Tyrosine Phosphorylation of Sperm Proteins and Altered Functional Dynamics of Buck Spermatozoa: an In Vitro Study

Present study was undertaken on buck spermatozoa to investigate the effect of mercuric chloride on functional dynamics of buck spermatozoa. Four different concentrations (0.031, 0.125, 0.25 and 1.25 μg/mL) of mercuric chloride, which were 1/40 th , 1/10 th , 1/5 th and equivalent to the LC 50 value...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biological trace element research 2020-12, Vol.198 (2), p.478-492
Hauptverfasser:	Kushawaha, Bhawna, Yadav, Rajkumar Singh, Swain, Dilip Kumar, Rai, Pradeep K, Garg, Satish Kumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrosome reaction Antioxidants Biochemistry Biomedical and Life Sciences Biotechnology Calcium (intracellular) Calcium ions Capacitation Chloride Chlorides Cyclic AMP Dynamics Exposure Intracellular Life Sciences Membrane potential Membranes Mercuric chloride Mercury Mercury (metal) Mercury compounds Mitochondria Mortality causes Nutrition Oncology Oxidative stress Phosphorylation Proteins Reactive oxygen species Semen Sperm Spermatozoa Superoxide dismutase Toxicity tests Tyrosine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Present study was undertaken on buck spermatozoa to investigate the effect of mercuric chloride on functional dynamics of buck spermatozoa. Four different concentrations (0.031, 0.125, 0.25 and 1.25 μg/mL) of mercuric chloride, which were 1/40 th , 1/10 th , 1/5 th and equivalent to the LC 50 value of HgCl 2 , were selected for studying their effect following in vitro exposure for 15 min and 3 h. Exposure of spermatozoa to 0.031 μg/mL mercuric chloride for 3 h resulted in significant ( p
ISSN:	0163-4984 1559-0720
DOI:	10.1007/s12011-020-02077-z