Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents

Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents

A new series of 1,3,4-oxadiazole incorporated imidazo[1,5- a ]pyridine derivatives was prepared. Anticancer activity of all the obtained compounds was investigated by employing MTT assay. Among them, six compounds showed most prominent anticancer activity than etoposide.

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Veröffentlicht in:Russian journal of general chemistry 2022-05, Vol.92 (5), p.891-897
Hauptverfasser: Srilaxmi, Dandamudi, Reddy, Alugubelli Gopi, Sireesha, Reddymasu, Rao, Pasupuleti Visweswara, Kiran, M. Ravi, Kolli, Deepti, Rao, Mandava Venkata Basaveswara
Format: Artikel
Sprache:eng
Schlagworte:
Anticancer properties
Cancer
Care and treatment
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Etoposide
Oxadiazoles
Pyridine
Pyridines
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Zusammenfassung:A new series of 1,3,4-oxadiazole incorporated imidazo[1,5- a ]pyridine derivatives was prepared. Anticancer activity of all the obtained compounds was investigated by employing MTT assay. Among them, six compounds showed most prominent anticancer activity than etoposide.
ISSN:1070-3632
1608-3350
DOI:10.1134/S107036322205019X