Medical management of open pyometra in a giant panda (Ailuropoda melanoleuca)

The female giant panda (Ailuropoda melanoleuca) has a characteristic reproductive physiology that involves a defined breeding season, embryonic diapause and potential for pseudopregnancy. The hormonal variation related to these reproductive characteristics may be a factor contributing to reproductive pathologies. In this case report, open pyometra was diagnosed in a giant panda. Clinical signs included lethargy, anorexia and mucopurulent vulvar discharge. Diagnostic tests performed included complete blood cell count, plasma biochemistry, protein electrophoresis, cytology, culture and sensitivity and abdominal ultrasonography. Treatment consisted of systemic antibiotics based on culture and sensitivity. Response to treatment was monitored via ultrasonography and visual examination of the vulvar region. Two weeks after treatment, the pyometra resolved and no subsequent complications were seen. This is the first case of pyometra reported in a giant panda. Pyometra should be considered as a differential diagnosis in entire female giant pandas presenting with abnormal clinical signs following breeding season.