Synergic Synthesis and Characterization of tert-Butyl 4-[(E)-But-1-en-3-yn-1-yl]-3-{[tert-butyl(dimethyl)silyl]oxy}-1H-indole-1-carboxylate
tert -Butyl 4-[( E )-but-1-en-3-yn-1-yl]-3-{[ tert -butyl(dimethyl)silyl]oxy}-1 H -indole-1-carboxylate has been synthesized with a good yield and selectivity starting from commercially available 4-bromo-1 H -indole and using simple reagents. The title compound is a potential precursor to biological...
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Veröffentlicht in: | Russian journal of organic chemistry 2022-04, Vol.58 (4), p.580-583 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
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Zusammenfassung: | tert
-Butyl 4-[(
E
)-but-1-en-3-yn-1-yl]-3-{[
tert
-butyl(dimethyl)silyl]oxy}-1
H
-indole-1-carboxylate has been synthesized with a good yield and selectivity starting from commercially available 4-bromo-1
H
-indole and using simple reagents. The title compound is a potential precursor to biologically active natural products like Indiacen A and Indiacen B. The newly synthesized compounds were characterized by spectral data. |
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ISSN: | 1070-4280 1608-3393 |
DOI: | 10.1134/S1070428022040169 |