Synthesis of tetracyclic thienotriazolopyridines based on hydrazine derivatives of fused pyridinethiones

A method for the synthesis of hydrazine derivatives of fused pyridinethiones based on alicyclic and heterocyclic ketones has been developed. Successive heterocyclization of these hydrazine derivatives was carried out in order to obtain new derivatives of tricyclic triazolo[4,3- a ]pyridines, tetracyclic thieno[3,2- e ][1,2,4]triazolo[4,3- a ]pyridines, as well as a new heterocyclic system of thieno[2,3- c ][1,2,4]triazolo[3,4- a ]-2,7-naphthyridine.