A New Triterpene from Metadina trichotoma

A New Triterpene from Metadina trichotoma

One new triterpene, 6α-hydroxyilexosapogenin A ( 1 ), and nine known compounds were isolated from Metadina trichotoma. Their structures were mainly elucidated by NMR and MS spectra. As evidenced by a glucose concentration assay, compound 2 can stimulate glucose uptake in 3T3-L1 adipocytes and is the...

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Veröffentlicht in:Chemistry of natural compounds 2022-03, Vol.58 (2), p.297-300
Hauptverfasser: Fan, Bin-Bin, Liu, Jia-Xiang, Hu, Hai-Jun, Zhang, Yu-Mei
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Dextrose
Glucose
NMR
Nuclear magnetic resonance
Organic Chemistry
Plant Sciences
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Zusammenfassung:One new triterpene, 6α-hydroxyilexosapogenin A ( 1 ), and nine known compounds were isolated from Metadina trichotoma. Their structures were mainly elucidated by NMR and MS spectra. As evidenced by a glucose concentration assay, compound 2 can stimulate glucose uptake in 3T3-L1 adipocytes and is the first pyrocincholic acid type triterpenoid that shows promoting glucose uptake activity.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-022-03663-4