Enantiomerically pure tetrahydroisoquinolines from the gold-catalysed isomerization of substrates derived from furans and amino acids

Enantiomerically pure tetrahydroisoquinolines from the gold-catalysed isomerization of substrates derived from furans and amino acids

A new route to enantiomerically pure 8-hydroxytetrahydroisoquinolines is based on furan derivatives and amino acids from renewable resources and gold catalysis. The stereogenic centre from the amino acid remains unchanged in the product.

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Bibliographische Detailangaben
Veröffentlicht in:Topics in catalysis 2007-06, Vol.44 (1-2), p.245-251
Hauptverfasser: Hashmi, A. Stephen K., Ata, Filiz, Kurpejovic, Elzen, Huck, Jürgen, Rudolph, Matthias
Format: Artikel
Sprache:eng
Schlagworte:
Amino acids
Furans
Gold
Isomerization
Renewable resources
Substrates
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Beschreibung
Zusammenfassung:A new route to enantiomerically pure 8-hydroxytetrahydroisoquinolines is based on furan derivatives and amino acids from renewable resources and gold catalysis. The stereogenic centre from the amino acid remains unchanged in the product.
ISSN:1022-5528
1572-9028
DOI:10.1007/s11244-007-0297-5