Stereoselective routes towards the synthesis of unusual bis(amino acids) and cyclic amino acids

SummaryStereoselective syntheses are described of bridged bis(glycines) as conformationally constrained substitutes for cystine, and of cyclic α-amino acids where the α-carbon of the amino acid is part of a five-, six- or seven-membered ring which may hold a hydroxy group as a threonine analogue.

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Veröffentlicht in:International journal of peptide research and therapeutics 1998-05, Vol.5 (2-3), p.227-233
1. Verfasser: Undheim, Kjell
Format: Artikel
Sprache:eng
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Zusammenfassung:SummaryStereoselective syntheses are described of bridged bis(glycines) as conformationally constrained substitutes for cystine, and of cyclic α-amino acids where the α-carbon of the amino acid is part of a five-, six- or seven-membered ring which may hold a hydroxy group as a threonine analogue.
ISSN:0929-5666
1573-3149
1573-496X
1573-3904
DOI:10.1007/BF02443474