Hair-bearing skin grown in a dish

[...]if the approach reaches the clinic, individuals who have wounds, scars and genetic skin diseases will have access to revolutionary treatments. For this type of cell-based approach to advance further, grafted skin must include more of the components found in normal skin: hair follicles, pigment-...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nature (London) 2020-06, Vol.582 (7812), p.343-344
Hauptverfasser: Wang, Leo L, Cotsarelis, George
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:[...]if the approach reaches the clinic, individuals who have wounds, scars and genetic skin diseases will have access to revolutionary treatments. For this type of cell-based approach to advance further, grafted skin must include more of the components found in normal skin: hair follicles, pigment-producing melanocyte cells, sweat glands, nerves, muscle, fat and immune cells, in addition to epidermal cells. Organoids have been grown to imitate various organs, including the gut, lung, kidney and brain7. Because organs consist of many cell types, organoids are typically formed from pluripotent stem cells, which have the ability to form all adult cell types.
ISSN:0028-0836
1476-4687
DOI:10.1038/d41586-020-01568-2