The In Vitro Effect of Alternating Currents on the Crystallogenic Properties of Blood Serum

—The purpose of this study was to assess the modification of the intrinsic crystal formation of blood serum under the action of alternating currents of different frequencies (40, 100 kHz, and 1 MHz). An experiment was carried out on ten samples of blood serum from practically healthy individuals; each sample was divided into four portions: a control and three experimental portions, which were treated with alternating current at a frequency of 40, 100, and 1000 kHz. The effect of exposure was assessed by the crystalloscopy method using morphological and morphometric analysis. It was found that the effect of alternating current on human blood serum samples led to a modification of the crystallogenic activity of the biological fluid, which manifested itself both in qualitative changes in the morphological pattern (facies) and in shifts in morphometric parameters (crystallizability, structural index, degree of the facies destruction, and clarity of the edge of the protein zone). At the same time, it has been shown that the dependence of this modulating effect depends on the frequency response; moreover, the most pronounced shifts of crystalloscopic parameters relative to the control sample, which was not subjected to any manipulation, were found for a frequency of 40 kHz, while minimum shifts occurred at a frequency of 1 MHz.