Complexes based on citrus pectin for delivery of tetracycline

The formation of complexes of sodium polygalacturonate with the antimicrobial drug tetracycline was confirmed by UV spectroscopy, powder X-ray diffraction, and dynamic light scattering. The stoichiometry of the complexes with the maximum tetracycline content (6.68 wt.%) was determined. The morpholog...

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Veröffentlicht in:	Russian chemical bulletin 2022-03, Vol.71 (3), p.549-556
Hauptverfasser:	Chekunkov, E. V., Minzanova, S. T., Khabibullina, A. V., Arkhipova, D. M., Mironova, L. G., Gubaidullin, A. T., Ryzhkina, I. S., Murtazina, L. I., Milyukov, V. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiinfectives and antibacterials Chemistry Chemistry and Materials Science Chemistry/Food Science Full Articles Inorganic Chemistry Light diffraction Organic Chemistry Pectin Photon correlation spectroscopy Stoichiometry X ray powder diffraction
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The formation of complexes of sodium polygalacturonate with the antimicrobial drug tetracycline was confirmed by UV spectroscopy, powder X-ray diffraction, and dynamic light scattering. The stoichiometry of the complexes with the maximum tetracycline content (6.68 wt.%) was determined. The morphological characteristics of the synthesized complexes were studied by scanning electron microscopy in comparison with the initial compounds.
ISSN:	1066-5285 1573-9171
DOI:	10.1007/s11172-022-3447-9