Nilotinib shows prolonged intracellular accumulation upon pulse-exposure: a novel mechanism for induction of apoptosis in CML cells

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Bibliographische Detailangaben
Veröffentlicht in:	Leukemia 2013-07, Vol.27 (7), p.1567-1570
Hauptverfasser:	Wagner, M-C, Dziadosz, M, Melo, J V, Heidel, F, Fischer, T, Lipka, D B
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1059 631/80/82/23 631/92/436/108 692/699/67/1990/283/1896 Apoptosis Apoptosis - drug effects Cancer Research Cell culture Cell death Cell Line, Tumor Chronic myeloid leukemia Critical Care Medicine Drug dosages Drug therapy Enzyme inhibitors Health aspects Hematology Humans Intensive Internal Medicine Investigations Kinases letter-to-the-editor Letters to the editor Leukemia Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology Medicine Medicine & Public Health Nilotinib Oncology Phosphorylation Protein Kinase Inhibitors - pharmacokinetics Pulse Therapy, Drug Pyrimidines - pharmacokinetics
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