Hepatotoxicity profile of single agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia, its impact on clinical outcome and the effect of genetic polymorphisms on the incidence of hepatotoxicity

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Bibliographische Detailangaben
Veröffentlicht in:	Leukemia 2006-05, Vol.20 (5), p.881-883
Hauptverfasser:	Mathews, V, Desire, S, George, B, Lakshmi, K M, Rao, J G, Viswabandya, A, Bajel, A, Srivastava, V M, Srivastava, A, Chandy, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute promyeloid leukemia Adult Arsenic Arsenic trioxide Arsenicals - administration & dosage Arsenicals - adverse effects Arsenicals - therapeutic use Cancer Research Chemical and Drug Induced Liver Injury - complications Chemical and Drug Induced Liver Injury - drug therapy Chemical and Drug Induced Liver Injury - etiology Cohort Studies Critical Care Medicine Disease-Free Survival Female Follow-Up Studies Gene polymorphism Genetic Predisposition to Disease Hematology Hepatotoxicity Humans Incidence Intensive Internal Medicine letter-to-the-editor Leukemia Leukemia, Promyelocytic, Acute - diagnosis Leukemia, Promyelocytic, Acute - drug therapy Leukemia, Promyelocytic, Acute - genetics Liver - drug effects Liver - enzymology Liver - pathology Liver Function Tests Male Medicine Medicine & Public Health Methylenetetrahydrofolate Reductase (NADPH2) - genetics Oncology Oxides - administration & dosage Oxides - adverse effects Oxides - therapeutic use Polymorphism, Genetic Promyeloid leukemia Remission Induction Risk Factors Survival Rate Treatment Outcome
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