Clinical significance of pretransplant serum ferritin on the outcome of allogeneic hematopoietic SCT: a prospective cohort study by the Kanto Study Group for Cell Therapy

Clinical significance of pretransplant serum ferritin on the outcome of allogeneic hematopoietic SCT: a prospective cohort study by the Kanto Study Group for Cell Therapy

This prospective study aimed to investigate the influence of pretransplant serum ferritin levels on the outcomes of allogeneic hematopoietic SCT (HSCT). In total, 190 patients with acute leukemia or myelodysplastic syndrome were consecutively enrolled. The patients were divided into two groups: low-...

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Veröffentlicht in:Bone marrow transplantation (Basingstoke) 2015-05, Vol.50 (5), p.727-733
Hauptverfasser: Tanaka, M, Kanamori, H, Matsumoto, K, Tachibana, T, Numata, A, Ohashi, K, Kobayashi, T, Nakaseko, C, Kanda, Y, Yamazaki, E, Fujisawa, S, Ooi, J, Sakura, T, Aotsuka, N, Onoda, M, Machida, S, Kato, J, Usuki, K, Watanabe, R, Taguchi, J, Yano, S, Saito, T, Takahashi, S, Sakamaki, H, Okamoto, S
Format: Artikel
Sprache:eng
Schlagworte:
692/308/2779/109/2154
Adult
Aged
Allografts
Analysis
Austria
Bacterial diseases
Bacterial Infections - blood
Bacterial Infections - mortality
Bone marrow
Care and treatment
Cell Biology
Cell therapy
Clinical significance
Cohort analysis
Disease-Free Survival
Female
Ferritin
Ferritins - blood
Follow-Up Studies
Health aspects
Hematologic Neoplasms - blood
Hematologic Neoplasms - mortality
Hematologic Neoplasms - therapy
Hematology
Hematopoietic Stem Cell Transplantation
Humans
Incidence
Infections
Internal Medicine
Leukemia
Male
Medicine
Medicine & Public Health
Middle Aged
Mortality
Mycoses - blood
Mycoses - mortality
Myelodysplastic syndrome
Myelodysplastic syndromes
Neutrophils
original-article
Patients
Preoperative Period
Prospective Studies
Public Health
Risk factors
Stem cell transplantation
Stem Cells
Survival Rate
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Zusammenfassung:This prospective study aimed to investigate the influence of pretransplant serum ferritin levels on the outcomes of allogeneic hematopoietic SCT (HSCT). In total, 190 patients with acute leukemia or myelodysplastic syndrome were consecutively enrolled. The patients were divided into two groups: low-ferritin group (
ISSN:0268-3369
1476-5365
DOI:10.1038/bmt.2015.17