Anti-Hyperglycemic effect of Polyherbal Formulation in Glucose Loaded and Epinephrine Induced Hyperglycemic Wistar rats

The poly herbal plant extracts were efficient in reducing the elevated glucose level than the independent use of plants. The poly herbal formulation were containing the extracts of Syzgium cumini, Annona squamosa, Momordica charantia, Tinospora cordifolia, Gymnema sylvestre and Curcuma longa. This poly herbal formulation was studied for anti-hyperglycemic activity in the glucose loaded and epinepharine induced hyperglycemic rats. The animal were divided into 5 groups each group had 6 animals; group no 1 was positive control, group no2, 3, 4 were different dose of poly herbal formulation PHF 225 mg/kg, PHF 450 mg/kg and PHF 850 mg/kg respectively and group no 5 was treated by Metformin 500mg/kg. The rats were treated for a period of 7 days, blood glucose level and biochemical parameters were measured on 7thday. The polyherbal formulation significantly (p