Acid-Base Properties of 6-Methyluracil-5-carbonitrile and Its N-Methyl Derivatives

The constants of acid-base equilibrium of 6-methyluracil-5-carbonitrile in water were determined spectrophotometrically. For the first time, 1,6-dimethyluracil-5-carbonitrile and 3,6-dimethyluracil-5-carbonitrile were obtained, their structures were proved by 1 H, 13 C, and 15 N NMR spectroscopy. Ba...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Russian journal of general chemistry 2022-02, Vol.92 (2), p.154-160
Hauptverfasser:	Akhiyarov, A. A., Lobov, A. N., Chernikova, I. B., Ivanov, S. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid base equilibrium Aqueous solutions Chemistry Chemistry and Materials Science Chemistry/Food Science NMR spectroscopy Nuclear magnetic resonance spectroscopy Spectrophotometry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The constants of acid-base equilibrium of 6-methyluracil-5-carbonitrile in water were determined spectrophotometrically. For the first time, 1,6-dimethyluracil-5-carbonitrile and 3,6-dimethyluracil-5-carbonitrile were obtained, their structures were proved by 1 H, 13 C, and 15 N NMR spectroscopy. Based on the p K a values obtained for all three compounds, the sequence of dissociation in the 6-methyluracil-5-carbonitrile molecule in alkaline aqueous solutions was determined.
ISSN:	1070-3632 1608-3350
DOI:	10.1134/S1070363222020037