Role of denosumab before resection and reconstruction in giant cell tumors of bone: a single-centered retrospective cohort study

Background Denosumab has been approved by Food and Drug Authority in 2013 for use in surgically unresectable Giant cell tumor (GCT) to achieve resectable tumor margins. The aim of this study is to investigate the functional outcome and surgical convenience with the use of neoadjuvant denosumab befor...

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Veröffentlicht in:	European journal of orthopaedic surgery & traumatology 2022-04, Vol.32 (3), p.567-574
Hauptverfasser:	Sahito, Badaruddin, Ali, Sheikh Muhammad Ebad, Kumar, Dileep, Kumar, Jagdesh, Hussain, Nauman, Lakho, Tahir
Format:	Artikel
Sprache:	eng
Schlagworte:	Biopsy Bone cancer Bone Density Conservation Agents - therapeutic use Bone Neoplasms - drug therapy Bone Neoplasms - pathology Bone Neoplasms - surgery Bone surgery Cohort analysis Denosumab - therapeutic use Drug dosages Fractures Giant Cell Tumor of Bone - drug therapy Giant Cell Tumor of Bone - pathology Giant Cell Tumor of Bone - surgery Humans Medicine Medicine & Public Health Monoclonal antibodies Neoplasm Recurrence, Local Original Article Orthopedics Patients Quality of Life Retrospective Studies Surgical Orthopedics Surgical techniques Traumatic Surgery Tumors
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