Hip abductor weakness in anti‐signal recognition particle antibody‐positive myopathy

A 40‐year‐old man presented with a 3‐month history of progressive weakness of the four limbs. On examination, weakness of the hip abductor was marked. While walking, shoulder sway was noted as a compensation for hip abductor weakness. Blood tests showed a marked elevation of creatine kinase (CK) lev...

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Veröffentlicht in:Neurology and clinical neuroscience 2022-03, Vol.10 (2), p.102-104
Hauptverfasser: Yamada, Takayuki, Kobayashi, Zen, Inoue, Keisuke, Tomimitsu, Hiroyuki
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Sprache:eng
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Zusammenfassung:A 40‐year‐old man presented with a 3‐month history of progressive weakness of the four limbs. On examination, weakness of the hip abductor was marked. While walking, shoulder sway was noted as a compensation for hip abductor weakness. Blood tests showed a marked elevation of creatine kinase (CK) level and the presence of anti‐signal recognition particle (SRP) antibodies. Thigh muscle MRI demonstrated the presence of inflammation in various muscles including the gluteus medius. Clinicians should consider the possibility of anti‐SRP antibody‐positive myopathy in patients presenting with hip abductor weakness in a subacute onset.
ISSN:2049-4173
2049-4173
DOI:10.1111/ncn3.12578