A New Phenanthrene Derivative with α-Glucosidase Inhibitory Activity from Pleione maculata

A New Phenanthrene Derivative with α-Glucosidase Inhibitory Activity from Pleione maculata

A new phenanthrene, 2,3,7-trihydroxy-4,8-dimethoxyphenanthrene ( 1 ), was isolated from Pleione maculata . Its structure was determined on the basis of NMR (1D and 2D) and HR-ESI-MS data. The new compound was also evaluated for its α -glucosidase inhibitory activity. Compared with the positive contr...

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Veröffentlicht in:Chemistry of natural compounds 2022, Vol.58 (1), p.6-8
Hauptverfasser: Li, Yu-Peng, Chen, Ya-Ping, Chen, Xing-Long, Tao, Yong-Sheng, Zhang, Rong-Ping
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Glucosidase
NMR
Nuclear magnetic resonance
Organic Chemistry
Phenanthrene
Plant Sciences
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Zusammenfassung:A new phenanthrene, 2,3,7-trihydroxy-4,8-dimethoxyphenanthrene ( 1 ), was isolated from Pleione maculata . Its structure was determined on the basis of NMR (1D and 2D) and HR-ESI-MS data. The new compound was also evaluated for its α -glucosidase inhibitory activity. Compared with the positive control, the new compound even slightly exceeded the effect of acarbose.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-022-03587-z