How to look for intracranial calcification in children with neurological disorders: CT, MRI, or both of them?

Background Intracranial calcification (ICC) is an important diagnostic clue in pediatric neurology. Considering the radiation-induced cancer risk associated with computed tomography (CT), we aim to define the diagnostic value of magnetic resonance imaging (MRI) sequences sensitive to paramagnetic/di...

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Veröffentlicht in:	Neurological sciences 2022-03, Vol.43 (3), p.2043-2050
Hauptverfasser:	Tonduti, Davide, Pichiecchio, Anna, Uggetti, Carla, Bova, Stefania Maria, Orcesi, Simona, Parazzini, Cecilia, Chiapparini, Luisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcification Calcification (ectopic) Calcinosis - complications Calcinosis - diagnostic imaging Child Children Computed tomography Humans Magnetic resonance imaging Magnetic Resonance Imaging - methods Medical imaging Medicine Medicine & Public Health Nervous System Diseases - diagnostic imaging Nervous System Diseases - etiology Neuroimaging Neurological diseases Neurological disorders Neurology Neuroradiology Neurosciences Neurosurgery Original Article Patients Pediatrics Psychiatry Scanning Tomography, X-Ray Computed
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Zusammenfassung:	Background Intracranial calcification (ICC) is an important diagnostic clue in pediatric neurology. Considering the radiation-induced cancer risk associated with computed tomography (CT), we aim to define the diagnostic value of magnetic resonance imaging (MRI) sequences sensitive to paramagnetic/diamagnetic substances in the detection of ICC, comparing with CT scanning. Materials and methods We selected MRI and CT scans performed in children affected by neurological conditions associated with ICC referred to the participating centers between 2005 and 2018. Inclusion criteria were age at neuroradiological investigation
ISSN:	1590-1874 1590-3478
DOI:	10.1007/s10072-021-05510-w