Low‐Cost Transition Metal‐Catalyzed Heck‐Type Reactions: An Overview
Heck coupling has emerged as an effective and powerful tool for C−C bond formations, with applications in academic and industrial grounds. The conventional Mizoroki‐Heck reaction employed expensive Pd based catalysts, however, developments to meet low‐cost replacements to Pd is relevant from a susta...
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Veröffentlicht in: | European journal of organic chemistry 2022-02, Vol.2022 (7), p.n/a |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Heck coupling has emerged as an effective and powerful tool for C−C bond formations, with applications in academic and industrial grounds. The conventional Mizoroki‐Heck reaction employed expensive Pd based catalysts, however, developments to meet low‐cost replacements to Pd is relevant from a sustainable point of view. Heck‐type couplings involving cost‐effective transition metals such as Fe, Co, Ni, and Cu have been established in the recent decades. Herein, we have comprehended the developments in low‐cost transition metal‐catalyzed Heck couplings covering the literature from 2016.
The Heck reaction for carbon‐carbon bond formation is one of the most studied coupling reactions in synthetic organic chemistry. These reactions have been widely used for the synthesis of a diverse range of heterocycles that find application in pharmaceutical and agrochemical industries. This review comprehends the developments in low‐cost transition metal‐catalyzed Heck couplings covering the literature from 2016 to today. |
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ISSN: | 1434-193X 1099-0690 |
DOI: | 10.1002/ejoc.202101384 |