A Novel Aloe Vera-Loaded Ethylcellulose/Hydroxypropyl Methylcellulose Nanofibrous Mat Designed for Wound Healing Application

Newly, the usage of nanofibers (NFs) as wound dressings with the aim of their rapid healing and prevention of bacterial infection has been considered by researchers. In this regard, we produced the ethylcellulose/hydroxypropyl methylcellulose NFs incorporated with Aloe-vera (EC/HPMC/Alv) by the elec...

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Veröffentlicht in:	Journal of polymers and the environment 2022-03, Vol.30 (3), p.867-877
Hauptverfasser:	Mohebian, Zahra, Tajmohammadi, Issa, Yavari Maroufi, Leila, Ramezani, Soghra, Ghorbani, Marjan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aloe Bacterial diseases Bacterial infections Biocompatibility Biodegradation Cell growth Cell proliferation Cell viability Cellulose Chemistry Chemistry and Materials Science Cytotoxicity E coli Environmental Chemistry Environmental Engineering/Biotechnology Ethyl cellulose Industrial Chemistry/Chemical Engineering Infections Materials Science Mechanical properties Medical dressings Methylcellulose Nanofibers Nutrition research Original Paper Polyethylene glycol Polymer Sciences Polymers Polyvinyl alcohol Research centers Toxicity Wound healing
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Zusammenfassung:	Newly, the usage of nanofibers (NFs) as wound dressings with the aim of their rapid healing and prevention of bacterial infection has been considered by researchers. In this regard, we produced the ethylcellulose/hydroxypropyl methylcellulose NFs incorporated with Aloe-vera (EC/HPMC/Alv) by the electrospinning technique. The produced NFs were investigated for their chemical structure, morphological, mechanical, degradation, swelling, cell viability, and antibacterial properties. Amongst the produced NFs, the NF samples containing 10% Alv illustrated the appropriate mechanical properties. The produced NFs did not show any cell cytotoxicity which indicates their good compatibility. Also, NFs containing Alv significantly (P
ISSN:	1566-2543 1572-8919
DOI:	10.1007/s10924-021-02240-0