5-acyl- and 5-nitroso-6-aminouraciles as starting reagents in the synthesis of 1,3,7,9-tetramethylpyrimidopteridine-2,4,6,8-tetraone

5-acyl- and 5-nitroso-6-aminouraciles as starting reagents in the synthesis of 1,3,7,9-tetramethylpyrimidopteridine-2,4,6,8-tetraone

Heating of 5-acetyl-1,3-dimethyluracil in TFA or in acetic acid with the addition of sulfuric acid resulted in ipso-substitution of the acyl group in the molecule. 5-Nitroso-1,3-dimethyluracil was transformed into 1,3,7,9-tetramethylpyrimidopteridine-2,4,6,8-tetraone by heating in TFA.

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Bibliographische Detailangaben
Hauptverfasser: Azev, Yu. A., Koptyaeva, O. S., Pospelova, T. A., Bakulev, V. A.
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Acetic acid
Heating
Reagents
Sulfuric acid
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Zusammenfassung:Heating of 5-acetyl-1,3-dimethyluracil in TFA or in acetic acid with the addition of sulfuric acid resulted in ipso-substitution of the acyl group in the molecule. 5-Nitroso-1,3-dimethyluracil was transformed into 1,3,7,9-tetramethylpyrimidopteridine-2,4,6,8-tetraone by heating in TFA.
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0069345