Relationship between Inflammatory Parameter and Mortality in Intensive Care Patients with COVID-19

We aimed to examine the relationship between hypoxemia, inflammatory parameters, cytokine storm and mortality in the COVID-19 Intensive Care Unit. COVID-19 patients followed in intensive care unit between 21 March and 1 June 2020 were retrospectively analyzed. Inflammatory parameters (CRP, ferritin,...

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Veröffentlicht in:Eastern journal of medicine 2022-01, Vol.27 (1), p.146-154
Hauptverfasser: Dereli, Necla, Babayiǧit, Munire, Koç, Filiz, Özbek, Özlem, Yildiz, Gokhan, Karasahin, Merve, Gursozlu, Ozge, Çakar, Nur Sena
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Sprache:eng
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Zusammenfassung:We aimed to examine the relationship between hypoxemia, inflammatory parameters, cytokine storm and mortality in the COVID-19 Intensive Care Unit. COVID-19 patients followed in intensive care unit between 21 March and 1 June 2020 were retrospectively analyzed. Inflammatory parameters (CRP, ferritin, D Dimer, leukocyte and lymphocyte, LDH...) were measured in blood samples taken simultaneously. The relationship of these parameters with mortality was evaluated. Of the 30 patients, 11 (36.7%) were female, 19 (63.3%) were male. When living (Group 1) and dead (Group 2) patient groups were compared, a statistically significant difference was found between the groups in terms of mean age (p = 0.013). It was observed that PaO2 / FiO2 ratios were lower in Group 2 in all measurements starting from the day of hospitalization in intensive care. While there was no difference between CRP and procalcitonin values in the first week, the 12th and last day measurements were found to be statistically significantly higher in Group 2 (respectively p2 = 0.050, p2 = 0.016; p2 = 0.050, p2
ISSN:1301-0883
1309-3886
DOI:10.5505/ejm.2022.00086