Mechanochemistry Enabled Construction of Isoxazole Skeleton via CuO Nanoparticles Catalyzed Intermolecular Dehydrohalogenative Annulation

Mechanochemistry Enabled Construction of Isoxazole Skeleton via CuO Nanoparticles Catalyzed Intermolecular Dehydrohalogenative Annulation

A dehydrohalogenative approach for isoxazole annulation by partnering β‐vinyl halides and α‐nitrocarbonyls under mechanochemical setting was accomplished. This chemistry is operative under the cooperative catalysis of cupric oxide nanoparticles (

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Veröffentlicht in:Advanced synthesis & catalysis 2021-11, Vol.363 (21), p.4941-4952
Hauptverfasser: Vadivelu, Murugan, Sampath, Sugirdha, Muthu, Kesavan, Karthikeyan, Kesavan, Praveen, Chandrasekar
Format: Artikel
Sprache:eng
Schlagworte:
Alkynes
Catalysis
Catalytic activity
Chemical reactions
Copper oxides
CuO nanocatalysis
Dehydrohalogenative annulation
Halides
Isoxazoles
Mechanochemistry
Nanoparticles
Organic chemistry
Reaction time
Reagents
Selectivity
Solvent-free conditions
Substrates
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Zusammenfassung:A dehydrohalogenative approach for isoxazole annulation by partnering β‐vinyl halides and α‐nitrocarbonyls under mechanochemical setting was accomplished. This chemistry is operative under the cooperative catalysis of cupric oxide nanoparticles (
ISSN:1615-4150
1615-4169
DOI:10.1002/adsc.202100730