Evaluation of antimycobacterial, antioxidant, and anticancer activities of CuO nanoparticles through cobalt doping

Here, we report the synthesis of cobalt-doped copper oxide nanoparticles (CuO–NPs) via combustion strategy with lime juice as a reductant at relatively low temperature of 600 °C and at shorter duration of 3 h. Powder X-ray diffraction (XRD) results revealed that, every compound was in monoclinic structure with space group C 12 /C 1 (No. 15) and average particle size were found to be 18–21 nm. These NPs were used to evaluate the antimycobacterial activity against “ Mycobacterium tuberculosis H37Rv ATCC 27294” , “ Mycobacterium abscessus ATCC 19977” , “ Mycobacterium fortuitum ATCC 6841” , “ Mycobacterium chelonae ATCC 35752” and anticancer activity on MDA-MB-231 . Antioxidant activity was evaluated by DPPH method. The results showed that, doping CuO with cobalt improved the antimycobacterial, anticancer and scavenging activities of CuO–NPs.