Molecular detection of M. tuberculosis and M. bovis and hematological and biochemical analyses in agricultural sprayers exposed to pesticides: A cross-sectional study in Punjab, Pakistan during 2014–2016

We determined the correlation between a pesticide exposure, physical health and susceptibility toward tuberculosis along with hematological indices and liver enzymes’ alterations in sprayers exposed to pesticides. Molecular detection of Mycobacterium tuberculosis and Mycobacterium bovis was detected...

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Veröffentlicht in:	Journal of exposure science & environmental epidemiology 2017-07, Vol.27 (4), p.434-443
Hauptverfasser:	Riaz, Saffora, Manzoor, Farkhanda, Mahmood, Nasir, Shahid, Saman
Format:	Artikel
Sprache:	eng
Schlagworte:	692/699/255/1856 692/700/3160 692/700/478/174 704/172/169/895 Adult Agriculture Agrochemicals Agrochemicals - adverse effects Alanine Alanine Transaminase - blood Analysis of Variance Aspartate Aminotransferases - blood Chi-square test Cross-Sectional Studies Enzymes Epidemiology Erythrocytes Exposure Female Hematology Histones Humans Immune system Leukocytes Leukocytes (neutrophilic) Liver Male Males Medicine Medicine & Public Health Middle Aged Mycobacterium bovis Mycobacterium bovis - isolation & purification Mycobacterium tuberculosis Mycobacterium tuberculosis - isolation & purification Occupational exposure Occupational Exposure - adverse effects original-article Pakistan Pesticide toxicity Pesticides Pesticides - adverse effects Polymerase Chain Reaction Sequence Analysis Sprayers Statistical tests Surveys and Questionnaires Tuberculosis Young Adult
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Zusammenfassung:	We determined the correlation between a pesticide exposure, physical health and susceptibility toward tuberculosis along with hematological indices and liver enzymes’ alterations in sprayers exposed to pesticides. Molecular detection of Mycobacterium tuberculosis and Mycobacterium bovis was detected by targeting histone-like protein ( hupB ) gene. The WBC (white blood cells) and RBC (red blood cells) levels of male sprayers and non-sprayers were significantly different ( P
ISSN:	1559-0631 1559-064X
DOI:	10.1038/jes.2016.88