Preparation of Silica Radiation Pore and Its Application as Antimicrobial Carrier

Hollow silica nanospheres with radical pore on the surfaces were prepared using the assemblies of valine amphiphilic small molecule and benzene as double-templates through sol-gel method in tetramethylammonium hydroxide (25wt%) solution at the stirring rate of 1 000 rpm. There are a lot of vertical pores on the surfaces of the hollow spheres after removing the templates in Muffle furnace at 550 °C for 5 h. The sample was characterized using field-emission scanning electron microscopy, transmission electron microscopy, Brunauer-Emmett-Teller (BET), X-ray diffraction, etc. The diameter, the vertical pore size of the nanospheres and the BET surface areas are 30–100 nm, 4.2 nm, and 570.5 m 2 /g, respectively. Because the high porosity and specific surface area, this kind of hollow sphere is the excellent antimicrobial carrier. The antibacterial activities of the silica nanospheres were evaluated by using a bacterial growth inhibitory assay. The experimental results show that the silica hollow spheres loaded with Ag + have a good bactericidal effect.