Evaluation of the Bioactive Properties of the Mineral-Polymer Composite Calcium Phosphates – Polylactide
The bioresorption and bioactivity of hybrid composite materials containing calcium phosphates up to 60 wt.% and polylactide (PLA) were studied in situ and in vitro . The resorption dynamics of composites in the PBS model environment was determined. It was found that at calcium phosphate content equa...
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Veröffentlicht in: | Glass and ceramics 2021-11, Vol.78 (7-8), p.317-322 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | The bioresorption and bioactivity of hybrid composite materials containing calcium phosphates up to 60 wt.% and polylactide (PLA) were studied
in situ
and
in vitro
. The resorption dynamics of composites in the PBS model environment was determined. It was found that at calcium phosphate content equal to 40% or more apatite-type calcium phosphates are produced on the surface of composites during incubation in SBF. Composites in the studied range of compositions have a weak cytotoxic effect on the cell culture of Neuro-2a mouse neuroblastoma. The data obtained suggest dynamic resorption and bioactivity of composites
in vivo
. |
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ISSN: | 0361-7610 1573-8515 |
DOI: | 10.1007/s10717-021-00402-z |