Pharmaceutical Interventions in an Intensive Care Unit of Covid-19 in Morocco

Objective/Aim: The objective of the study was to analyze pharmaceutical interventions and their impact in patients hospitalized in an intensive care unit of Covid-19 in a Moroccan university hospital center. Methods: The study was initiated in an intensive care unit at Ibn Sina hospital in Rabat for a period of three months between November and February 2021. The prescriptions were analyzed and validated according to the methodology of the French Society of Clinical Pharmacy (SFPC). The clinical impact was evaluated according to the Hatoum scale. Results: During the study period, corresponding to three months, 71 IP are identified with an acceptance rate of 99%. The sex ratio (M/F) was 1.7 in a favour of male predominance. The average age of our patients was 63 years. The main prescription problems encountered were overdose (34%), non-compliance with consensus (29%), under dosing (13%), and drug interaction (13%). Our interventions concerned dosage adjustment (52%), substitution/exchange (15%), therapeutic follow-up (12%), and drug withdrawal (8%). 98% of the interventions had a non-zero impact. Conclusion: This study highlights the importance of the clinical pharmacist in the fight against drug-related harm especially in the context of the pandemic where vigilance is required.