Invasive Candidiasis in Liver Transplant Recipients: A Review
Purpose of Review This review summarizes the literature on invasive candidiasis (IC) in liver transplant recipients (LTRs) regarding diagnostic strategies, treatment, and prophylaxis. Recent Findings Recent literature on IC has expanded and refined definitions of risk factors for IC in LTRs. We disc...
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| Veröffentlicht in: | Current fungal infection reports 2021-12, Vol.15 (4), p.151-161 |
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| container_title | Current fungal infection reports |
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| creator | Sigler, Rachel Aslam, Saima |
| description | Purpose of Review
This review summarizes the literature on invasive candidiasis (IC) in liver transplant recipients (LTRs) regarding diagnostic strategies, treatment, and prophylaxis.
Recent Findings
Recent literature on IC has expanded and refined definitions of risk factors for IC in LTRs. We discuss increasing rates of resistance among candida species and new antifungals. Diagnostic modalities continue to decrease time to initiation of empiric antifungals, which may impact outcomes.
Summary
A well-documented host of risk factors for IC may allow for targeted prophylaxis, while minimizing exposure to antifungal medications. Further research on minimum effective duration of treatment and prophylaxis is needed to combat resistance. |
| doi_str_mv | 10.1007/s12281-021-00426-6 |
| format | Article |
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This review summarizes the literature on invasive candidiasis (IC) in liver transplant recipients (LTRs) regarding diagnostic strategies, treatment, and prophylaxis.
Recent Findings
Recent literature on IC has expanded and refined definitions of risk factors for IC in LTRs. We discuss increasing rates of resistance among candida species and new antifungals. Diagnostic modalities continue to decrease time to initiation of empiric antifungals, which may impact outcomes.
Summary
A well-documented host of risk factors for IC may allow for targeted prophylaxis, while minimizing exposure to antifungal medications. Further research on minimum effective duration of treatment and prophylaxis is needed to combat resistance.</description><identifier>ISSN: 1936-3761</identifier><identifier>EISSN: 1936-377X</identifier><identifier>DOI: 10.1007/s12281-021-00426-6</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Candidiasis ; Disease prevention ; Fungal Infections in Transplantation (S Shoham ; Infectious Diseases ; Internal Medicine ; Liver transplantation ; Liver transplants ; Medicine ; Medicine & Public Health ; Occupational Medicine/Industrial Medicine ; Pneumology/Respiratory System ; Prophylaxis ; Reviews ; Risk factors ; Section Editor ; Topical Collection on Fungal Infections in Transplantation ; Tropical Medicine</subject><ispartof>Current fungal infection reports, 2021-12, Vol.15 (4), p.151-161</ispartof><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021</rights><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c270t-65d7b965de7719c2ef9e6b9c16e6404f35c77af2ee1971a601e71448b455a1923</cites><orcidid>0000-0002-8861-1150</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12281-021-00426-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12281-021-00426-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids></links><search><creatorcontrib>Sigler, Rachel</creatorcontrib><creatorcontrib>Aslam, Saima</creatorcontrib><title>Invasive Candidiasis in Liver Transplant Recipients: A Review</title><title>Current fungal infection reports</title><addtitle>Curr Fungal Infect Rep</addtitle><description>Purpose of Review
This review summarizes the literature on invasive candidiasis (IC) in liver transplant recipients (LTRs) regarding diagnostic strategies, treatment, and prophylaxis.
Recent Findings
Recent literature on IC has expanded and refined definitions of risk factors for IC in LTRs. We discuss increasing rates of resistance among candida species and new antifungals. Diagnostic modalities continue to decrease time to initiation of empiric antifungals, which may impact outcomes.
Summary
A well-documented host of risk factors for IC may allow for targeted prophylaxis, while minimizing exposure to antifungal medications. Further research on minimum effective duration of treatment and prophylaxis is needed to combat resistance.</description><subject>Candidiasis</subject><subject>Disease prevention</subject><subject>Fungal Infections in Transplantation (S Shoham</subject><subject>Infectious Diseases</subject><subject>Internal Medicine</subject><subject>Liver transplantation</subject><subject>Liver transplants</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Occupational Medicine/Industrial Medicine</subject><subject>Pneumology/Respiratory System</subject><subject>Prophylaxis</subject><subject>Reviews</subject><subject>Risk factors</subject><subject>Section Editor</subject><subject>Topical Collection on Fungal Infections in Transplantation</subject><subject>Tropical Medicine</subject><issn>1936-3761</issn><issn>1936-377X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9UE1LAzEUDKJgrf4BTwueV_Py2QgeSrFaKAhSwVvI7r6VlJquybbivze6ojcP72MeM_NgCDkHegmU6qsEjE2gpCwXFUyV6oCMwHBVcq2fD393BcfkJKU1pQq04SNyswh7l_wei5kLjW98BqnwoVjmWyxW0YXUbVzoi0esfecx9Om6mGa09_h-So5at0l49jPH5Gl-u5rdl8uHu8VsuixrpmlfKtnoyuSOWoOpGbYGVWVqUKgEFS2XtdauZYhgNDhFATUIMamElA4M42NyMfh2cfu2w9Tb9XYXQ35pmaJiIrlUMrPYwKrjNqWIre2if3XxwwK1XzHZISabY7LfMVmVRXwQpUwOLxj_rP9RfQLCmmkC</recordid><startdate>20211201</startdate><enddate>20211201</enddate><creator>Sigler, Rachel</creator><creator>Aslam, Saima</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0002-8861-1150</orcidid></search><sort><creationdate>20211201</creationdate><title>Invasive Candidiasis in Liver Transplant Recipients: A Review</title><author>Sigler, Rachel ; Aslam, Saima</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c270t-65d7b965de7719c2ef9e6b9c16e6404f35c77af2ee1971a601e71448b455a1923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Candidiasis</topic><topic>Disease prevention</topic><topic>Fungal Infections in Transplantation (S Shoham</topic><topic>Infectious Diseases</topic><topic>Internal Medicine</topic><topic>Liver transplantation</topic><topic>Liver transplants</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Occupational Medicine/Industrial Medicine</topic><topic>Pneumology/Respiratory System</topic><topic>Prophylaxis</topic><topic>Reviews</topic><topic>Risk factors</topic><topic>Section Editor</topic><topic>Topical Collection on Fungal Infections in Transplantation</topic><topic>Tropical Medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sigler, Rachel</creatorcontrib><creatorcontrib>Aslam, Saima</creatorcontrib><collection>CrossRef</collection><jtitle>Current fungal infection reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sigler, Rachel</au><au>Aslam, Saima</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Invasive Candidiasis in Liver Transplant Recipients: A Review</atitle><jtitle>Current fungal infection reports</jtitle><stitle>Curr Fungal Infect Rep</stitle><date>2021-12-01</date><risdate>2021</risdate><volume>15</volume><issue>4</issue><spage>151</spage><epage>161</epage><pages>151-161</pages><issn>1936-3761</issn><eissn>1936-377X</eissn><abstract>Purpose of Review
This review summarizes the literature on invasive candidiasis (IC) in liver transplant recipients (LTRs) regarding diagnostic strategies, treatment, and prophylaxis.
Recent Findings
Recent literature on IC has expanded and refined definitions of risk factors for IC in LTRs. We discuss increasing rates of resistance among candida species and new antifungals. Diagnostic modalities continue to decrease time to initiation of empiric antifungals, which may impact outcomes.
Summary
A well-documented host of risk factors for IC may allow for targeted prophylaxis, while minimizing exposure to antifungal medications. Further research on minimum effective duration of treatment and prophylaxis is needed to combat resistance.</abstract><cop>New York</cop><pub>Springer US</pub><doi>10.1007/s12281-021-00426-6</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0002-8861-1150</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1936-3761 |
| ispartof | Current fungal infection reports, 2021-12, Vol.15 (4), p.151-161 |
| issn | 1936-3761 1936-377X |
| language | eng |
| recordid | cdi_proquest_journals_2604853565 |
| source | SpringerLink Journals - AutoHoldings |
| subjects | Candidiasis Disease prevention Fungal Infections in Transplantation (S Shoham Infectious Diseases Internal Medicine Liver transplantation Liver transplants Medicine Medicine & Public Health Occupational Medicine/Industrial Medicine Pneumology/Respiratory System Prophylaxis Reviews Risk factors Section Editor Topical Collection on Fungal Infections in Transplantation Tropical Medicine |
| title | Invasive Candidiasis in Liver Transplant Recipients: A Review |
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