Prevalence of Diabetes Mellitus and Correlation of Urinary Transforming Growth Factor-b1 with Blood Hemoglobin A1C in the Atascosa Diabetes Study

The authors present a study conducted to determine the prevalence of type 2 diabetes and prediabetes in the Atascosa Diabetes Study sample and to ascertain the relationship between urinary transforming growth factor-b1 (TGF-b1) and blood hemoglobin (Hgb) A1C. Subjects classified as adjusted normal, at risk, prediabetes, and diabetes mellitus were given a one-hour and two-hour postprandial glucose (PPG) test. Morning urine samples were collected to test for a correlation of TGF-b1 with blood HgbA1C. Of the subjects, 14.3% had diabetes, 31.6% had prediabetes, 7.9% were at risk, and 46.2% were adjusted normal, the author explain. The percentage of subjects with type 2 diabetes was 1.64 times higher than the national average. Prevalence of prediabetes was equivalent in Hispanics and Whites, and the reversal for diabetes might reflect higher mortality rate from diabetes in Hispanics in Atascosa County.