Purine adducts as a presumable missing link for aristolochic acid nephropathy‐related cellular energy crisis, potential anti‐fibrotic prevention and treatment
Aristolochic acid nephropathy is a progressive exposome‐induced disease characterized by tubular atrophy and fibrosis culminating in end‐stage renal disease and malignancies. The molecular mechanisms of the energy crisis as a putative cause of fibrosis have not yet been elucidated. In light of the f...
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Veröffentlicht in: | British journal of pharmacology 2021-11, Vol.178 (22), p.4411-4427 |
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Sprache: | eng |
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