Quantifying and dispensing of magnetic particles in a self-assembled magnetic particle array
•Magnetic particles serve as general-purpose tools for personalized medicine.•Low-cost, mass-production process of magnetic particles for IVD industrialization.•Quantifying and dispensing of magnetic particles using magnetic self-assembly.•Automatic dispenser as magnetic particles packaging technolo...
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Veröffentlicht in: | Journal of magnetism and magnetic materials 2021-12, Vol.539, p.168341, Article 168341 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | •Magnetic particles serve as general-purpose tools for personalized medicine.•Low-cost, mass-production process of magnetic particles for IVD industrialization.•Quantifying and dispensing of magnetic particles using magnetic self-assembly.•Automatic dispenser as magnetic particles packaging technology.
We develop a low-cost, mass-production process for creating rod-shaped glass-coated magnetic particles consisting of a magnetic metal core and glass shell structure. We investigate their magnetic properties by analyzing their optical absorbance in suspension as a function of the orientation of a 1 mT magnetic field. From the response we derive that the magnetization of the particles is 0.1 MA/m. We demonstrate an automated system that quantifies and dispenses a large amount of RGMPs by magnetic self-assembly on a high-volume plate patterned with an array of holes. This automatic dispenser can provide packaging forms with the smallest unit of RGMPs for in-vitro diagnostics and is expected to reduce the time and effort required for the assembly and packaging process. |
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ISSN: | 0304-8853 1873-4766 |
DOI: | 10.1016/j.jmmm.2021.168341 |