Quantifying and dispensing of magnetic particles in a self-assembled magnetic particle array

•Magnetic particles serve as general-purpose tools for personalized medicine.•Low-cost, mass-production process of magnetic particles for IVD industrialization.•Quantifying and dispensing of magnetic particles using magnetic self-assembly.•Automatic dispenser as magnetic particles packaging technolo...

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Veröffentlicht in:Journal of magnetism and magnetic materials 2021-12, Vol.539, p.168341, Article 168341
Hauptverfasser: Song, Suk-Heung, Yoon, Jinsik, Jeong, Yongkyo, Jung, Yong-Gyun, Abelmann, Leon, Park, Wook
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Sprache:eng
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Zusammenfassung:•Magnetic particles serve as general-purpose tools for personalized medicine.•Low-cost, mass-production process of magnetic particles for IVD industrialization.•Quantifying and dispensing of magnetic particles using magnetic self-assembly.•Automatic dispenser as magnetic particles packaging technology. We develop a low-cost, mass-production process for creating rod-shaped glass-coated magnetic particles consisting of a magnetic metal core and glass shell structure. We investigate their magnetic properties by analyzing their optical absorbance in suspension as a function of the orientation of a 1 mT magnetic field. From the response we derive that the magnetization of the particles is 0.1 MA/m. We demonstrate an automated system that quantifies and dispenses a large amount of RGMPs by magnetic self-assembly on a high-volume plate patterned with an array of holes. This automatic dispenser can provide packaging forms with the smallest unit of RGMPs for in-vitro diagnostics and is expected to reduce the time and effort required for the assembly and packaging process.
ISSN:0304-8853
1873-4766
DOI:10.1016/j.jmmm.2021.168341