Functional magnetic nanoparticles for use in a drug delivery system

γ-Fe2O3 nanoparticles encapsulated in amorphous SiO2 were prepared by the wet chemical method and carboxyl-modified functionalized nanoparticles were produced. The prepared samples were examined by X-ray diffraction measurements and TEM images. Particles sizes in the range 4-20 nm were determined fr...

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Veröffentlicht in:Journal of physics. Conference series 2010-01, Vol.200 (12), p.122003
Hauptverfasser: Hiroki, Tomoyuki, Taira, Shu, Katayanagi, Hikaru, Moro, Yuki, Shigeoka, Daiki, Kimura, Shinji, Mashino, Toshiyuki, Ichiyanagi, Yuko
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Sprache:eng
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Zusammenfassung:γ-Fe2O3 nanoparticles encapsulated in amorphous SiO2 were prepared by the wet chemical method and carboxyl-modified functionalized nanoparticles were produced. The prepared samples were examined by X-ray diffraction measurements and TEM images. Particles sizes in the range 4-20 nm were determined from the Scherrer formula. Magnetization was measured by a SQUID magnetometer under a ±50-kOe magnetic field. The magnetization curves showed ferromagnetic or superparamagnetic behaviour depending on particle size. Functionalized nanoparticles were confirmed by Fourier transform infrared spectroscopy (FT-IR) measurements. The typical C=O peak was detected in the spectrum of functionalized nanoparticles. These magnetic nanoparticles are expected to be used as carriers in drug delivery systems (DDS), hyperthermia treatment, and other biomedical applications.
ISSN:1742-6596
1742-6588
1742-6596
DOI:10.1088/1742-6596/200/12/122003