Preparation of an Adduct of Levoglucosenone and Resorcinol and its in vitro Antiplatelet and Anticoagulant Activity

Preparation of an Adduct of Levoglucosenone and Resorcinol and its in vitro Antiplatelet and Anticoagulant Activity

A procedure for the preparation of an adduct of levoglucosenone and resorcinol was developed involving ultrasonic irradiation in the presence of K 2 CO 3 and 18-crown-6 ether in toluene. In vitro anticoagulant and antiplatelet activity of the adduct was studied.

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Veröffentlicht in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2021-09, Vol.57 (9), p.966-969
Hauptverfasser: Faizullina, Liliya Kh, Khalilova, Yuliya А., Valeev, Farid А., Pavlov, Valentin N., Samorodov, Aleksandr V.
Format: Artikel
Sprache:eng
Schlagworte:
Anticoagulants
Anticoagulants (Medicine)
Chemistry
Chemistry and Materials Science
Crown ethers
Organic Chemistry
Pharmacy
Potassium carbonate
Short Communication
Toluene
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Zusammenfassung:A procedure for the preparation of an adduct of levoglucosenone and resorcinol was developed involving ultrasonic irradiation in the presence of K 2 CO 3 and 18-crown-6 ether in toluene. In vitro anticoagulant and antiplatelet activity of the adduct was studied.
ISSN:0009-3122
1573-8353
DOI:10.1007/s10593-021-03007-0