Synthesis of 5-(hydroxy-, chloro-, bromomethyl)furan-2-enones Based on Fructose and their Antioxidant Activity

New enones were synthesized from 5-hydroxymethylfurfurol (5-HMF) and its derivatives using Wittig reactions of various phosphoranes. The synthesized enones were observed to affect free-radical oxidation in model systems, in particular, to suppress generation of reactive oxygen species.

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Veröffentlicht in:Chemistry of natural compounds 2021-09, Vol.57 (5), p.869-874
Hauptverfasser: Sakhautdinova, G. F., Malikova, R. N., Bortsova, Yu. L., Mochalov, K. S., Muratov, E. M., Galimova, E. F., Sakhautdinov, I. M., Mustafin, A. G.
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Sprache:eng
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Zusammenfassung:New enones were synthesized from 5-hydroxymethylfurfurol (5-HMF) and its derivatives using Wittig reactions of various phosphoranes. The synthesized enones were observed to affect free-radical oxidation in model systems, in particular, to suppress generation of reactive oxygen species.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-021-03500-0