Hepatoprotective activity of ethyl acetate fraction from Lygodium microphyllum leaves in CCl4 induced damage rats

Lygodium microphyllum is one of the plants that have the potential as an agent hepatoprotective because known of these plants have been used as the chinese traditional medicine. They use it to treat hepatitis diseases with drink a stew of the plant. The purpose of this study is to study the effects of a ethyl acetate fraction as hepatoprotective from L. microphyllum leaves in CCl4 induced damaged rats. This study uses animals of about 36 rats divided into six groups for 14 days. On the 15th-day, animal testing sacrificed and extracted the blood and surely to know the activity of the SGOT and SGPT and hold the histological structure of the liver to know the liver damage. The result showed the idea of a fraction of ethyl acetate leaves L. microphyllum may lower levels of SGOT significantly (p