Pruritus in liver disease – pathenogenisis and treatment

Pruritus in liver disease – pathenogenisis and treatment

Pruritus often constitutes a most irritating ailment in patients suffering from chronic liver diseases, especially when cholestasis plays a prominent role. The exact pathogenesis is not entirely recognized. Nevertheless, several mechanisms have been proposed: pruritus connected with a central/periph...

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Veröffentlicht in:Journal of pre-clinical and clinical research 2011, Vol.5 (2), p.47
Hauptverfasser: Michalak, Agata, Hanc, Magdalena, Fatyga, Aleksandra, Skublewska, Aleksandra, Prystupa, Andrzej, Mosiewicz, Jerzy
Format: Review
Sprache:eng
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Gallbladder diseases
Pathogenesis
Pruritus
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container_title Journal of pre-clinical and clinical research
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creator Michalak, Agata
Hanc, Magdalena
Fatyga, Aleksandra
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Mosiewicz, Jerzy
description Pruritus often constitutes a most irritating ailment in patients suffering from chronic liver diseases, especially when cholestasis plays a prominent role. The exact pathogenesis is not entirely recognized. Nevertheless, several mechanisms have been proposed: pruritus connected with a central/peripheral origin, itch caused by mast cells’ hyperactivity, or determined by the intrahepatic cholestasis of pregnancy. This article concentrates on the pruritus accompanying advanced liver disorders. Its pathogenesis and treatment are also discussed.
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source DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals
subjects Gallbladder diseases
Pathogenesis
Pruritus
title Pruritus in liver disease – pathenogenisis and treatment
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