Reaction of arylglyoxal hydrate derivatives with cyanoguanidine under benzilic rearrangement effect

Reaction of arylglyoxal hydrate derivatives with cyanoguanidine under benzilic rearrangement effect

A novel series of (5-aryl-4-oxoimidazolidin-2-ylidene)cyanamides was successfully synthesized via the reaction of arylglyoxal hydrates with cyanoguanidine through benzilic rearrangement mechanism. The reaction was also optimized by changing various reaction factors for endeavor to increase the yield...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Monatshefte für Chemie 2021-10, Vol.152 (10), p.1285-1290
Hauptverfasser: Moustafa, Amr H., Hussein, Bahgat R. M.
Format: Artikel
Sprache:eng
Schlagworte:
Analytical Chemistry
Chemical synthesis
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Cyanamides
Hydrates
Inorganic Chemistry
Organic Chemistry
Original Paper
Physical Chemistry
Theoretical and Computational Chemistry
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A novel series of (5-aryl-4-oxoimidazolidin-2-ylidene)cyanamides was successfully synthesized via the reaction of arylglyoxal hydrates with cyanoguanidine through benzilic rearrangement mechanism. The reaction was also optimized by changing various reaction factors for endeavor to increase the yield of the target product and reduce the by-product 1-cyano-3-(2-oxo-2-arylethylidene)guanidine formation. Graphic abstract
ISSN:0026-9247
1434-4475
DOI:10.1007/s00706-021-02838-z