Specialized nanowhisker probes for high-precision investigation of native bio-objects in liquid by means of atomic force microscopy

Fabrication and investigation of specialized Pt-C single nanowhisker probes are carried out for high-precision study of objects with organic and inorganic nature in liquids by atomic force microscopy. The best modes and buffered media were revealed on calibration lattice TGQ1 choosing as reference inorganic structure. Preliminary results of the study of the structure of bacteria E.Coli in the native state were received in the PBS liquid. Fixation of the bacteria was performed on agar-agar with a mass fraction of 1.8%. The significant improvement of image contrast and resolution was found when using nanowhisker probes compare to standard Si tips.