Aplasia Cutis Congenita and Other Anomalies Associated with Methimazole Exposure During Pregnancy

: Aplasia cutis congenita (ACC) is a congenital defect consisting of a circumscribed absence of skin that usually involves the scalp. The etiology is uncertain, and several teratogenic agents such as methimazole have been involved. We report two cases of ACC and other anomalies in newborns exposed...

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Veröffentlicht in:	Pediatric dermatology 2011-11, Vol.28 (6), p.743-745
Hauptverfasser:	RODRÍGUEZ-GARCÍA, CRISTINA, GONZÁLEZ-HERNÁNDEZ, SORAHAYA, HERNÁNDEZ-MARTÍN, ANGELA, PÉREZ-ROBAYNA, NURIA, SÁNCHEZ, ROSALBA, TORRELO, ANTONIO
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antithyroid Agents - adverse effects Aplasia Biological and medical sciences Birth defects Congenital diseases Dermatology Drug therapy Ectodermal Dysplasia - chemically induced Etiology Female Fetuses Graves Disease - drug therapy Head Hereditary diseases of the skin. Congenital diseases of the skin. Haemangioma of the skin, of mucosae and of soft tissue Humans Hyperthyroidism Infant, Newborn Male Medical sciences Methimazole - adverse effects Neonates Pediatrics Pregnancy Prenatal development Prenatal Exposure Delayed Effects - chemically induced Propylthiouracil - adverse effects Scalp Scalp - abnormalities Skin diseases Teratogenicity Toxicity
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Zusammenfassung:	: Aplasia cutis congenita (ACC) is a congenital defect consisting of a circumscribed absence of skin that usually involves the scalp. The etiology is uncertain, and several teratogenic agents such as methimazole have been involved. We report two cases of ACC and other anomalies in newborns exposed to methimazole during pregnancy.
ISSN:	0736-8046 1525-1470
DOI:	10.1111/j.1525-1470.2011.01572.x