Guillain Barre vs. Miastenia Gravis as an Atypical Presentation of SARS COV 2 By Molecular Mimic: Purpose of a Case
Additionally, it is known that the pathophysiological mechanism of the entry of the virus into the cell, through the viral protein Spike, not only occurs through the receptor for the angiotensinconverting enzyme-2, but also uses glycoproteins and gangliosides that contain sialic acid on cell surface...
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Veröffentlicht in: | Health science journal 2021-01, Vol.15 (7), p.1-4 |
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Sprache: | eng |
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Zusammenfassung: | Additionally, it is known that the pathophysiological mechanism of the entry of the virus into the cell, through the viral protein Spike, not only occurs through the receptor for the angiotensinconverting enzyme-2, but also uses glycoproteins and gangliosides that contain sialic acid on cell surfaces. In the presentation of our case, we raised the SARS-CoV-2 infection as a possible triggering event of MG or GB in the patient, based on the theory of molecular mimicry as a possible cause of the condition, in light of this case in clinical practice, we reinforce the hypothesis of the association between Guillain-Barré/ Myasthenia Gravis syndrome and SARS-CoV-2 virus infection, as has already been documented by other authors. Case Report A 21-year-old woman from Talaigua Nuevo, Bolívar municipality, Republic of Colombia, who is admitted to the emergency service due to a sudden onset clinical picture of approximately 1 hour of evolution consisting of dysphagia, odynophagia, asthenia, episodes of dizziness, adynamia, accompanied by decreased muscle strength in upper limbs, also associated with loss of tongue sensitivity; Additionally, the patient states that the only symptom that he presented in the last days was an occasional dry cough with a predominance of the day. Hemodynamic instability, manifested by the appearance of sustained supraventricular tachycardia with deterioration So we proceed to perform orotracheal intubation and electrical cardioversion. pharmacological with satisfactory reversal and stabilization; Later, CPK, VDRL, HIV, Hepatitis B extension paraclinics, lumbar puncture with cytochemicals and culture of common germs of the cerebrospinal fluid and chest CT scan are requested. |
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ISSN: | 1791-809X 1791-809X |