1003-P: FINDRISC Identifies Diabetes Due to Insulin Resistance but Not ß-Cell Failure

Diabetes (DM) prediction scores such as the Finnish Diabetes Risk Score (FINDRISC) assume that insulin resistance (IR) is the cause of DM. Yet, data in Africans suggest β-cell failure rather than IR is often the cause of DM. It is unknown if FINDRISC's ability to predict DM differs when the cause is β-cell failure rather than IR. Our two goals in 181 Africans with Abnl-GT (a term for both DM and preDM) was to determine the prevalence of IR vs. β-cell failure and FINDRISC's ability to predict DM in each group. Diagnosis of AbnlGT-IR required both AbnlGT and HOMA-IR≥2.1. AbnlGT-β-cell-failure required both AbnlGT and HOMA-IR