23-OR: ADA Presidents’ Select Abstract: Genetic Architecture and Novel Genes Implicated in Youth-Onset Type 2 Diabetes

Youth-onset type 2 diabetes (T2D) has a strong genetic predisposition and is regarded as a phenotypic extreme of adult-onset T2D. In this study, we aimed to investigate the contribution of rare coding variants to the genetic basis of youth-onset T2D by analyzing whole-exome sequences of 3,005 person...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2021-06, Vol.70 (Supplement_1)
Hauptverfasser:	KWAK, SOO HEON, SRINIVASAN, SHYLAJA, CHEN, LING, TODD, JENNIFER, JENSEN, ELIZABETH T., DIVERS, JASMIN, MOTTL, AMY K., PIHOKER, CATHERINE, GANDICA, RACHELLE, LAFFEL, LORI M., ISGANAITIS, ELVIRA M., HAYMOND, MOREY W., LEVITSKY, LYNNE L., POLLIN, TONI I., FLOREZ, JOSE C., FLANNICK, JASON
Format:	Artikel
Sprache:	eng
Schlagworte:	Beta cells Diabetes Diabetes mellitus (non-insulin dependent) Genes Genetic diversity Insulin Insulin secretion
Online-Zugang:	Volltext
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