Synthesis and antibacterial activity of 2-((1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)ethyl acetate

Synthesis and antibacterial activity of 2-((1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)ethyl acetate

Derivatization of lawsone compound (1) was done by reacting it with ethanolamine to give 2-((2-hydroxyethyl)amino)-1,4-naphthoquinone (2), and then treating with acetic anhydride to produce the desired compound 2-((1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino) ethyl acetate (3). The target compound po...

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Veröffentlicht in:IOP conference series. Materials Science and Engineering 2020-02, Vol.763 (1), p.12011
Hauptverfasser: Cahyana, A H, Ardiansah, B, Widodo, A C
Format: Artikel
Sprache:eng
Schlagworte:
E coli
Ethyl acetate
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Zusammenfassung:Derivatization of lawsone compound (1) was done by reacting it with ethanolamine to give 2-((2-hydroxyethyl)amino)-1,4-naphthoquinone (2), and then treating with acetic anhydride to produce the desired compound 2-((1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino) ethyl acetate (3). The target compound possesses the antibacterial activity against E. coli and S. aureus.
ISSN:1757-8981
1757-899X
1757-899X
DOI:10.1088/1757-899X/763/1/012011