Green and Red Brazilian Propolis: Antimicrobial Potential and Anti‐Virulence against ATCC and Clinically Isolated Multidrug‐Resistant Bacteria

Brazilian green and red propolis stand out as commercial products for different medical applications. In this article, we report the antimicrobial activities of the hydroalcoholic extracts of green (EGP) and red (ERP) propolis, as well as guttiferone E plus xanthochymol (8) and oblongifolin B (9) fr...

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Veröffentlicht in:	Chemistry & biodiversity 2021-08, Vol.18 (8), p.e2100307-n/a
Hauptverfasser:	Souza Silva, Thayná, Silva, Júlia M. B., Braun, Gláucia H., Mejia, Jennyfer A. A., Ccapatinta, Gari V. C., Santos, Mário Ferreira Conceição, Tanimoto, Matheus H., Bastos, Jairo K., Parreira, Renato L. T., Orenha, Renato P., Borges, Alexandre, Berretta, Andresa A., Veneziani, Rodrigo C. S., Martins, Carlos H. G., Ambrósio, Sérgio R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids antibacterial activity Antiinfectives and antibacterials Antimicrobial agents Bacteria Biochemistry & Molecular Biology Biofilms Catalase Chemistry Chemistry, Multidisciplinary Coagulase Deoxyribonuclease green propolis guttiferone E Life Sciences & Biomedicine Minimum inhibitory concentration Molecular docking Multidrug resistant organisms oblongifolin Physical Sciences Propolis red propolis Science & Technology Virulence xanthochymol
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Beschreibung
Zusammenfassung:	Brazilian green and red propolis stand out as commercial products for different medical applications. In this article, we report the antimicrobial activities of the hydroalcoholic extracts of green (EGP) and red (ERP) propolis, as well as guttiferone E plus xanthochymol (8) and oblongifolin B (9) from red propolis, against multidrug‐resistant bacteria (MDRB). We undertook the minimal inhibitory (MIC) and bactericidal (MBC) concentrations, inhibition of biofilm formation (MICB50), catalase, coagulase, DNase, lipase, and hemolysin assays, along with molecular docking simulations. ERP was more effective by displaying MIC and MBC values
ISSN:	1612-1872 1612-1880
DOI:	10.1002/cbdv.202100307