Plasma Magnesium Concentrations and Risk of Incident Cancer in Adults with Hypertension: A Nested Case-Control Study

Plasma Magnesium Concentrations and Risk of Incident Cancer in Adults with Hypertension: A Nested Case-Control Study

Objective: The association between plasma magnesium and risk of incident cancer remains inconclusive in previous studies. We aimed to investigate the prospective relationship of baseline plasma magnesium concentrations with the risk of incident cancer and to examine possible effect modifiers. Method...

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Veröffentlicht in:Annals of nutrition and metabolism 2021-01, Vol.76 (5), p.304-312
Hauptverfasser: Lin, Tengfei, Bi, Chonglei, Song, Yun, Guo, Huiyuan, Liu, Lishun, Zhou, Ziyi, Wang, Binyan, Tang, Genfu, Liu, Chengzhang, Yang, Yan, Ling, Wenhua, Yang, Jingang, Cui, Yimin, Zhang, Chengguo, Li, Gang, Li, Jiaang, Li, Jianping, Zhang, Yan, Huo, Yong, Wang, Xiaobin, Zhang, Hao, Qin, Xianhui, Xu, Xiping
Format: Artikel
Sprache:eng
Schlagworte:
Adults
Aspirin
Blood pressure
Breast cancer
Cancer
Case studies
Cholesterol
Complications and side effects
Esophagus
Gastric cancer
Health aspects
Health risks
Hypertension
Lung cancer
Magnesium
Magnesium in the body
Measurement
Original Paper
Plasma
Quartiles
Risk
Risk factors
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Zusammenfassung:Objective: The association between plasma magnesium and risk of incident cancer remains inconclusive in previous studies. We aimed to investigate the prospective relationship of baseline plasma magnesium concentrations with the risk of incident cancer and to examine possible effect modifiers. Methods: A nested case-control study with 228 incident cancer cases and 228 matched controls was conducted using data from the China Stroke Primary Prevention Trial (CSPPT), a randomized, double-blind, controlled trial, conducted from May 2008 to August 2013. Study outcomes included incident cancer and its subtypes. Results: When plasma magnesium concentrations were assessed as quartiles, a significantly higher incident risk of total cancer was found in participants in quartile 1 (
ISSN:0250-6807
1421-9697
DOI:10.1159/000510214