Two‐Dimensional Metal‐Organic Framework Film for Realizing Optoelectronic Synaptic Plasticity

2D metal‐organic framework (MOF) film as the active layer show promising application prospects in various fields including sensors, catalysis, and electronic devices. However, exploring the application of 2D MOF film in the field of artificial synapses has not been implemented yet. In this work, we fabricated a novel 2D MOF film (Cu‐THPP, THPP=5,10,15,20‐Tetrakis(4‐hydroxyphenyl)‐21H,23H‐porphine), and further used it as an active layer to explore the application in the simulation of human brain synapses. It shows excellent light‐stimulated synaptic plasticity properties, and exhibits the foundation function of synapses such as long‐term plasticity (LTP), short‐term plasticity (STP), and the conversion of STP to LTP. Most critically, the MOF based artificial synaptic device exhibits an excellent stability in atmosphere. This work opens the door for the application of 2D MOF film in the simulation of human brain synapses. A novel MOF film (Cu‐THPP) is prepared and used as the active layer to simulate human memory synapses for the first time. It possesses satisfactory fundamental function of biological synaptic memory. This work demonstrates the tremendous application potential of 2D MOF films in artificial synaptic devices.