Association between early and late response in eyes with central or hemiretinal vein occlusion treated with anti-VEGF agents

Association between early and late response in eyes with central or hemiretinal vein occlusion treated with anti-VEGF agents

PurposeTo assess whether early visual acuity letter score change from baseline (ΔVALS) and early spectral domain optical coherence tomography (SD-OCT) measures of center point thickness (CPT) are associated with later ΔVALS in eyes with macular edema due to central or hemiretinal vein occlusion trea...

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Veröffentlicht in:Graefe's archive for clinical and experimental ophthalmology 2021-07, Vol.259 (7), p.1839-1851
Hauptverfasser: Khurana, Rahul N, Oden, Neal L, VanVeldhuisen, Paul C, Scott, Ingrid U, Blodi, Barbara A, Ip, Michael S
Format: Artikel
Sprache:eng
Schlagworte:
Acuity
Bevacizumab
Clinical trials
Diabetes
Diabetic retinopathy
Edema
Occlusion
Ophthalmology
Software
Vascular endothelial growth factor
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Zusammenfassung:PurposeTo assess whether early visual acuity letter score change from baseline (ΔVALS) and early spectral domain optical coherence tomography (SD-OCT) measures of center point thickness (CPT) are associated with later ΔVALS in eyes with macular edema due to central or hemiretinal vein occlusion treated with intravitreal aflibercept or bevacizumab.MethodsSecondary analysis of a randomized clinical trial of 362 participants.ResultsConsidered separately at month 3, CPT (categorized as ≤ 300 μm, > 300 μm) and ΔVALS (categorized as
ISSN:0721-832X
1435-702X
DOI:10.1007/s00417-020-05018-7